When dealing with sensitive pharmaceutical, scientific, and microprocessor manufacturing processes, a certain environment must be maintained at all times. These environments also referred to as clean rooms, are designed to accommodate such processes and technical functions. As such, these controlled work areas must pay attention to certain considerations during clean room design if they are to be utilized as intended. For instance, all clean rooms must maintain a controlled level of air particulates, as well as other contaminants in order for it to be considered appropriate for use. To help you out with your clean room design, here are important considerations to reflect on:
The class, regulations, and standards to be complied with
For a clean room to be considered compliant, it must meet certain regulations and standards that have been specified by the industry a company is involved in. A clean room to be utilized for sterilized compounding of dangerous drugs will have to meet different standards from a clean room to be used for microelectronics. In order for your clean room to receive the certification it requires; it must meet these set standards and regulations.
The needed operation conditions
A quality clean room must be able to meet the needed operating conditions for the sake of the processes to be carried out inside as well as for the comfort of the staff members working in the clean room. At a minimum, most cleanroom solutions must meet particular temperature, pressure and humidity, and differentials as well as a high-quality HVAC design. The air conditioning, especially, is of particular importance because the heat produced by the processes occurring inside as well as the heat produced by the personnel must be taken into account so that it can be compensated by the air conditioning system.
During the design process, the personnel, as well as the material flow within the clean room, must be paid attention to. The layout must be designed in such a manner that ensures that critical processes are kept separate and isolated from all the access doors and pathways to be utilized by staff members. The areas where the most critical processes are to be carried out should only be accessed using a single access point to prevent cross-contamination.
Such a layout is considered critical for any clean room that intends to deal with any pharmaceutical and biopharmaceutical processes. When designing the layout, companies must also remember to pay attention to flexibility and adaptability just in case they should want to expand or reconfigure the clean room in the future.